MedicalPersonalized Medicine

Merck and EOS sister company AMCM partner to 3D print tablets

Pharmaceutical company Merck and German custom additive manufacturing specialist AMCM (sister company of EOS) have announced a collaboration through which they will develop 3D printed tablet formulations. The partnership aims to create a tablet 3D printing process that conforms to Good Manufacturing Practice (GMP) standards for clinical trials and, eventually, for commercial manufacturing services.

3D printed pills are gaining traction in healthcare, as medical and drug companies realize the potential of additive manufacturing to personalize medicine and dosages. In this case, Merck is hoping to leverage 3D printing to achieve greater scalability for API (active pharmaceutical development) formulations by minimizing reliance on costly reformulations across the whole pharmaceutical development and production process. The pharma giant sees an opportunity to use 3D printing to create tablets in a more cost and time efficient manner.

Merck AMCM 3D printed tablets
Isabel de Paoli, Chief Strategy Officer at Merck

“Our partnership with AMCM/EOS has the potential to revolutionize the way tablets are produced. It will be a massive move towards digitalization of the industry,” commented Isabel de Paoli, Chief Strategy Officer at Merck. “Our goal is to develop the industrial application of this technology, which we will make available for clinical trials first, and then move to full digital solutions at commercial scale.”

Through the partnership, AMCM will supply a customized powder bed fusion process that will reportedly simplify the clinical development of drugs. The 3D printing technology is expected to pave the way to more flexible and sustainable tablet production, by enabling localized manufacturing that can address specific market requirements and by being adaptable to patient needs.

Marie Langer, CEO of EOS, said of the collaboration: “We are excited to support Merck on its innovation journey. This cooperation combines Merck’s formulation competences in Healthcare as well as its excipient expertise in Life Science with our long-standing additive manufacturing know-how. Together, we will help make drug development more flexible and faster.”

The 3D printed tablet project will be spearheaded by the Innovation Center at Merck’s headquarters in Darmstadt, Germany.

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Tess Boissonneault

Tess Boissonneault moved from her home of Montreal, Canada to the Netherlands in 2014 to pursue a master’s degree in Media Studies at the University of Amsterdam. It was during her time in Amsterdam that she became acquainted with 3D printing technology and began writing for a local additive manufacturing news platform. Now based in France, Tess has over two and a half years experience writing, editing and publishing additive manufacturing content with a particular interest in women working within the industry. She is an avid follower of the ever-evolving AM industry.

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