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Harvard researchers develop MM3D multi-nozzle printer that can switch between 8 inks in a blink

Possible applications in soft robotics, organ bioprinting and more

A new technique called MM3D (multimaterial multi-nozzle 3D) printing developed by Harvard’s Wyss Institute researchers uses high-speed pressure valves to achieve rapid, continuous, and seamless switching between up to eight different printing materials. This new technique enables the creation of complex shapes in a fraction of the time currently required using printheads that range from a single nozzle to large multi-nozzle arrays.

These 3D printheads themselves are manufactured using 3D printing, enabling their rapid customization and facilitating adoption by others in the fabrication community. Each nozzle is capable of switching materials at up to 50 times per second, which is faster than the eye can see, or about as fast as a hummingbird beats its wings.

 

Multi-nozzle applications for bioprinting

MM3D printing can also be used to create more complex objects, including actuating robots. The research team designed and printed a soft robot composed of rigid and soft elastomers in a millipede-like pattern that included embedded pneumatic channels that enable the soft “muscles” to be compressed sequentially by a vacuum, making the robot “walk.” The robot was able to move at nearly half an inch per second while carrying a load eight times its own weight and could be connected to other robots to carry heavier loads.

“3D printing is revolutionizing the manufacturing industry by allowing people to create without the need for expensive machinery and raw materials, and this new advance promises to dramatically improve the pace of innovation in this exciting area.”Donald Ingber, M.D., Ph.D., Wyss Founding Director

“This method enables the rapid design and fabrication of voxelated matter, which is an emerging paradigm in our field,” said corresponding author Jennifer A. Lewis, Sc.D., who is a Core Faculty Member at the Wyss Institute and the Hansjörg Wyss Professor of Biologically Inspired Engineering at SEAS. “Using our broad palette of functional, structural, and biological inks, disparate materials can now be seamlessly integrated into 3D-printed objects on-demand.”

The fact that Professor Lewis is involved in this research goes a long way to show that the ultimate goal for rapid and precise multi-nozzle 3D printing is biological tissue and organ printing. Professor Lewis is conducting some of the World’s most advanced research on material and biomaterials for extrusion 3D printing. One of the main limits in 3D printing of advanced organs is the ability to replicate the complex multi-material structure – including vascularity – using hydrogels without compromising cell activity. Other interesting potential applications, also previously demonstrated by Prof. Lewis and her team, focus on soft robotics.

Importantly, current MM3D printheads can only print periodic (i.e., repeating) parts. But the team envisions that MM3D printing will continue to evolve, eventually featuring nozzles that can extrude different inks at different times, smaller nozzles for greater resolution, and even larger arrays for rapid, single-step 3D printing at a wide range of size and resolution scales. They are also exploring the use of sacrificial inks to create even more complex shapes.

MM3D
Multimaterial multi-nozzle 3D (MM3D) printing can switch between up to eight different inks 50 times per second, allowing the creation of complex, high-quality 3D objects in a fraction of the time currently required by other extrusion-based printing methods. Credit: Wyss Institute at Harvard University

Why multi-material 3D printing at Wyss

3D printers are revolutionizing manufacturing by allowing users to create any physical shape they can imagine on-demand. However, most commercial printers are only able to build objects from a single material at a time and inkjet printers that are capable of multimaterial printing are constrained by the physics of droplet formation. Extrusion-based 3D printing allows a broad palette of materials to be printed, but the process is extremely slow. For example, it would take roughly 10 days to build a 3D object roughly one liter in volume at the resolution of a human hair and print speed of 10 cm/s using a single-nozzle, single-material printhead. To build the same object in less than 1 day, one would need to implement a printhead with 16 nozzles printing simultaneously.

“When printing an object using a conventional extrusion-based 3D printer, the time required to print it scales cubically with the length of the object, because the printing nozzle has to move in three dimensions rather than just one,” said co-first author Mark Skylar-Scott, Ph.D., a Research Associate at the Wyss Institute. “MM3D’s combination of multi-nozzle arrays with the ability to switch between multiple inks rapidly effectively eliminates the time lost to switching printheads and helps get the scaling law down from cubic to linear, so you can print multimaterial, periodic 3D objects much more quickly.”

MM3D
The printhead can accommodate multiple nozzles, each of which can print up to eight different materials. A series of branched channels distributes the “inks” to the nozzles. Credit: Lori K. Sanders

The key to MM3D printing’s speedy ink-switching is a series of Y-shaped junctions inside the printhead where multiple ink channels come together at a single output nozzle. The shape of the nozzle, printing pressure, and ink viscosity are all precisely calculated and tuned so that when pressure is applied to one of the “arms” of the junction, the ink that flows down through that arm does not cause the static ink in the other arm to flow backwards, which prevents the inks from mixing and preserves the quality of the printed object. By operating the printheads using a bank of fast pneumatic valves, this one-way flow behavior allows the rapid assembly of multimaterial filaments that flow continuously out from each nozzle and enables the construction of a 3D multimaterial part. The length of the ink channels can also be adjusted to account for materials that have different viscosities and yield stresses, and thus flow more quickly or slowly than other inks.

“Because MM3D printing can produce objects so quickly, one can use reactive materials whose properties change over time, such as epoxies, silicones, polyurethanes, or bio-inks,” said co-first author Jochen Mueller, Ph.D., a Research Fellow at the Wyss Institute and SEAS. “One can also readily integrate materials with disparate properties to create origami-like architectures or soft robots that contain both stiff and flexible elements.

MM3D
Rapid switching between inks is achieved thanks to special Y-shaped junctions in each nozzle (far left) that are precisely tuned to prevent mixing or backflow of the inks during printing. The junctions can be multiplexed for larger printing jobs, and can be customized to account for materials with different physical properties (second from right). Credit: Lori K. Sanders

To demonstrate their technique, the researchers printed a Miura origami structure composed of stiff “panel” sections connected by highly flexible “hinge” sections. Previous methods of building such a structure require manually assembling them together into stacked layers – the MM3D printhead was able to print the entire object in a single step by using eight nozzles to continuously extrude two alternating epoxy inks whose stiffnesses differed by four orders of magnitude after being cured. The hinges withstood over 1,000 folding cycles before failing, indicating the high quality of the transitions between the stiff and flexible materials achieved during printing.

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One Comment

  1. Harvard researchers create a wander again. Now they create a 3D printer that has multi nozzles. Due to many nozzles, it can switch between 8 inks. So the day is not far when the 3D printer will be the most popular and most important device in the world.

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