After 30 years of discoveries and over 10,000 citations, Corning Matrigel matrix has cemented its place as a trusted ECM in biology labs worldwide. Biologists, tissue engineers, and industry giants alike rely on Matrigel matrix as a foundational biomaterial for diverse applications, from cancer and stem cell research to neurobiology. Now it is possible to use Corning’s Matrigel matrix bioink on Allevi bioprinters.
Allevi’s 3D bioprinters use high-quality bioinks without the need for viscosity agents that can hinder ECM’s performance. The firm’s patented CORE printheads have been engineered to optimally print pure biomaterials, such as Matrigel matrix, so that users can continue working with the bioinks that they already know and trust, which is why Allevi worked with Corning Life Sciences to develop the first-ever protocol for bioprinting using Matrigel matrix.
Matrigel matrix, produced by Corning, is a natural ECM-based hydrogel derived from Engelbreth-Holm-Swarm (EHS) mouse sarcoma. This bioink is rich in ECM proteins such as laminin, collagen IV, heparan sulfate proteoglycans, entactin/nidogen, and a number of growth factors. This network of proteins provides the environment needed for optimal tissue performance, driving cellular responses such as proliferation and attachment.
Matrigel matrix has a unique formulation that when used with Allevi bioprinters allows ysers to create custom 3D tissues. This is an optimal platform for cells to differentiate and behave more closely to how they would in the human body. Matrigel matrix has been fueling 30 years of research. Now the pace of discovery is bound to quicken as a new dimension is added to this bioink.
In case you were wondering, Corning Life Sciences belongs to the same group as the Corning that makes Gorilla Glass and produces glass fiber filaments for extrusion 3D printers as well as glass-ceramic photopolymer resin materials for stereolithography processes. Although it has not yet established an AM division, now the company is active in yet another segment of 3D printing.